If a pear or most fruits
growing on a tree touch a branch or brush a branch in a breeze it can leave an abrasion on the skin which won't necessarily ruin the fruit.
But something penetrating through the skin and into the interior opens it to any thing looking for a home to grow in. And most fruit sugar content is a hospitable medium for many things.
Human skin is consistently regenerating. And performs an even more complex protective factor than does a simpler fruit skin.
I don't know of anything that could be applied that would heal the fruit skin.
Do you need to do this over a series of time and many fruit? If you only need one or two I would say go for it and experiment. And isolate it from the rest.